Planta Med 2004; 70(1): 68-69
DOI: 10.1055/s-2004-815459
Letter
© Georg Thieme Verlag Stuttgart · New York

Taraxer-14-en-3β-ol, an Anti-Inflammatory Compound from Sterculia foetida L.

D. G. Naik1 , A. M. Mujumdar1 , R. J. Waghole1 , A. V. Misar1 , S. W. Annie Bligh2 , Alan Bashall2 , John Crowder2
  • 1Agharkar Research Institute, Pune, India
  • 2Institute of Health Research and Policy, London Metropolitan University, London, U.K.
Further Information

Publication History

Received: July 23, 2003

Accepted: November 8, 2003

Publication Date:
06 February 2004 (online)

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Abstract

Taraxer-14-en-3β-ol (1) was shown to be the active ingredient in the leaves of Sterculia foetida L. The alcohol 1, its acetate and ketone showed anti-inflammatory activity against TPA induced mouse ear oedema with inhibition ratios of 60.0, 58.57 and 40.57 at 0.5 mg/ear, respectively. The percentage inhibition of inflammation increased with dose for each compound.

References

Dr. D. G. Naik

Chemistry Group

Agharkar Research Institute

Pune-411 004

India

Phone: +91-020-25653680

Fax: +91-020-25651542

Email: dgnpune@yahoo.co.in